L381-1295 Screening compound: 1-[6-({[(3-acetylphenyl)carbamoyl]methyl}sulfanyl)pyridazin-3-yl]-N-propylpiperidine-4-carboxamide

L381-1295 Screening compound: 1-[6-({[(3-acetylphenyl)carbamoyl]methyl}sulfanyl)pyridazin-3-yl]-N-propylpiperidine-4-carboxamide
L381-1295 Screening compound: 1-[6-({[(3-acetylphenyl)carbamoyl]methyl}sulfanyl)pyridazin-3-yl]-N-propylpiperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L381-1295
1-[6-({[(3-acetylphenyl)carbamoyl]methyl}sulfanyl)pyridazin-3-yl]-N-propylpiperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L381-1295

Molecular Formula

C23H29N5O3S (C23 H29 N5 O3 S)

Compound Name

1-[6-({[(3-acetylphenyl)carbamoyl]methyl}sulfanyl)pyridazin-3-yl]-N-propylpiperidine-4-carboxamide

IUPAC name

1-[6-({[(3-acetylphenyl)carbamoyl]methyl}sulfanyl)pyridazin-3-yl]-N-propylpiperidine-4-carboxamide

SMILES

CCCNC(C(CC1)CCN1c(cc1)nnc1SCC(Nc1cc(C(C)=O)ccc1)=O)=O

InChI

InChI=1S/C23H29N5O3S/c1-3-11-24-23(31)17-9-12-28(13-10-17)20-7-8-22(27-26-20)32-15-21(30)25-19-6-4-5-18(14-19)16(2)29/h4-8,14,17H,3,9-13,15H2,1-2H3,(H,24,31)(H,25,30)

InChI Key

QCFOPRXZXDNMJK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27248813

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.58

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.582

Distribution Coefficient, logD

2.581

Water Solubility, LogSw

-2.96

Polar Surface Area

85.489

Acid Dissociation Constant (pKa)

11.00

Base Dissociation Constant (pKb)

9.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

43.50

L381-1295 in Drug Discovery

Included in Screening Libraries

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L381-1295 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L381-1295?
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What is the minimum amount of L381-1295 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L381-1295
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L381-1295
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L381-1295 available by request