L385-0012 Screening compound: N-(3-ethylphenyl)-2-(4-oxo-2-phenyl-3,4-dihydro-5H-pyrido[2,3-b][1,4]diazepin-5-yl)acetamide

L385-0012 Screening compound: N-(3-ethylphenyl)-2-(4-oxo-2-phenyl-3,4-dihydro-5H-pyrido[2,3-b][1,4]diazepin-5-yl)acetamide
L385-0012 Screening compound: N-(3-ethylphenyl)-2-(4-oxo-2-phenyl-3,4-dihydro-5H-pyrido[2,3-b][1,4]diazepin-5-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L385-0012
N-(3-ethylphenyl)-2-(4-oxo-2-phenyl-3,4-dihydro-5H-pyrido[2,3-b][1,4]diazepin-5-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L385-0012

Molecular Formula

C24H22N4O2 (C24 H22 N4 O2)

Compound Name

N-(3-ethylphenyl)-2-(4-oxo-2-phenyl-3,4-dihydro-5H-pyrido[2,3-b][1,4]diazepin-5-yl)acetamide

IUPAC name

N-(3-ethylphenyl)-2-{4-oxo-2-phenyl-3H4H5H-pyrido[23-b][14]diazepin-5-yl}acetamide

SMILES

CCc1cccc(NC(CN(c2ncccc2N=C(C2)c3ccccc3)C2=O)=O)c1

InChI

InChI=1S/C24H22N4O2/c1-2-17-8-6-11-19(14-17)26-22(29)16-28-23(30)15-21(18-9-4-3-5-10-18)27-20-12-7-13-25-24(20)28/h3-14H,2,15-16H2,1H3,(H,26,29)

InChI Key

IFMJSEXNRREBFW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27249192

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.052

Distribution Coefficient, logD

4.052

Water Solubility, LogSw

-4.05

Polar Surface Area

58.070

Acid Dissociation Constant (pKa)

12.79

Base Dissociation Constant (pKb)

1.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.67

L385-0012 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L385-0012 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L385-0012?
Check Price and Availability of L385-0012, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L385-0012 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L385-0012
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L385-0012
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L385-0012 available by request