L385-0741 Screening compound: methyl 4-{2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate

L385-0741 Screening compound: methyl 4-{2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate
L385-0741 Screening compound: methyl 4-{2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L385-0741
methyl 4-{2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L385-0741

Molecular Formula

C24H19ClN4O4 (C24 H19 ClN4 O4)

Compound Name

methyl 4-{2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate

IUPAC name

methyl 4-{2-[2-(4-chlorophenyl)-4-oxo-3H4H5H-pyrido[23-b][14]diazepin-5-yl]acetamido}benzoate

SMILES

COC(c(cc1)ccc1NC(CN(c(nccc1)c1N=C(C1)c(cc2)ccc2Cl)C1=O)=O)=O

InChI

InChI=1S/C24H19ClN4O4/c1-33-24(32)16-6-10-18(11-7-16)27-21(30)14-29-22(31)13-20(15-4-8-17(25)9-5-15)28-19-3-2-12-26-23(19)29/h2-12H,13-14H2,1H3,(H,27,30)

InChI Key

KXIPHVFHCRHWFG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27249420

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.89

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.052

Distribution Coefficient, logD

4.052

Water Solubility, LogSw

-4.53

Polar Surface Area

79.244

Acid Dissociation Constant (pKa)

10.90

Base Dissociation Constant (pKb)

-0.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

L385-0741 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

SH2 Library (10483 compounds)

New Agro Library (44492 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Agro:
  • Agro
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L385-0741 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L385-0741?
Check Price and Availability of L385-0741, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L385-0741 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L385-0741
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L385-0741
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L385-0741 available by request