L385-0774 Screening compound: 2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]-N-(3,4,5-trimethoxyphenyl)acetamide

L385-0774 Screening compound: 2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]-N-(3,4,5-trimethoxyphenyl)acetamide
L385-0774 Screening compound: 2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]-N-(3,4,5-trimethoxyphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L385-0774
2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]-N-(3,4,5-trimethoxyphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L385-0774

Molecular Formula

C25H23ClN4O5 (C25 H23 ClN4 O5)

Compound Name

2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]-N-(3,4,5-trimethoxyphenyl)acetamide

IUPAC name

2-[2-(4-chlorophenyl)-4-oxo-3H4H5H-pyrido[23-b][14]diazepin-5-yl]-N-(345-trimethoxyphenyl)acetamide

SMILES

COc1cc(NC(CN(c(nccc2)c2N=C(C2)c(cc3)ccc3Cl)C2=O)=O)cc(OC)c1OC

InChI

InChI=1S/C25H23ClN4O5/c1-33-20-11-17(12-21(34-2)24(20)35-3)28-22(31)14-30-23(32)13-19(15-6-8-16(26)9-7-15)29-18-5-4-10-27-25(18)30/h4-12H,13-14H2,1-3H3,(H,28,31)

InChI Key

DWTFASBGUOWRRT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27249426

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

494.93

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.342

Distribution Coefficient, logD

3.341

Water Solubility, LogSw

-3.79

Polar Surface Area

81.048

Acid Dissociation Constant (pKa)

10.31

Base Dissociation Constant (pKb)

2.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

L385-0774 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L385-0774 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L385-0774?
Check Price and Availability of L385-0774, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L385-0774 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L385-0774
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L385-0774
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L385-0774 available by request