L385-0833 Screening compound: 2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]-N-[4-(trifluoromethyl)phenyl]acetamide

L385-0833 Screening compound: 2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]-N-[4-(trifluoromethyl)phenyl]acetamide
L385-0833 Screening compound: 2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]-N-[4-(trifluoromethyl)phenyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L385-0833
2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]-N-[4-(trifluoromethyl)phenyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L385-0833

Molecular Formula

C23H16ClF3N4O2 (C23 H16 ClF3 N4 O2)

Compound Name

2-[2-(4-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]-N-[4-(trifluoromethyl)phenyl]acetamide

IUPAC name

2-[2-(4-chlorophenyl)-4-oxo-3H4H5H-pyrido[23-b][14]diazepin-5-yl]-N-[4-(trifluoromethyl)phenyl]acetamide

SMILES

O=C(CN(c(nccc1)c1N=C(C1)c(cc2)ccc2Cl)C1=O)Nc1ccc(C(F)(F)F)cc1

InChI

InChI=1S/C23H16ClF3N4O2/c24-16-7-3-14(4-8-16)19-12-21(33)31(22-18(30-19)2-1-11-28-22)13-20(32)29-17-9-5-15(6-10-17)23(25,26)27/h1-11H,12-13H2,(H,29,32)

InChI Key

PNWVTLFLMIQOHS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27249432

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.85

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.834

Distribution Coefficient, logD

4.834

Water Solubility, LogSw

-5.07

Polar Surface Area

58.070

Acid Dissociation Constant (pKa)

12.47

Base Dissociation Constant (pKb)

-0.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

L385-0833 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L385-0833 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L385-0833?
Check Price and Availability of L385-0833, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L385-0833 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L385-0833
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L385-0833
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L385-0833 available by request