L385-0892 Screening compound: ethyl 2-{2-[2-(3-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate

L385-0892 Screening compound: ethyl 2-{2-[2-(3-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate
L385-0892 Screening compound: ethyl 2-{2-[2-(3-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L385-0892
ethyl 2-{2-[2-(3-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L385-0892

Molecular Formula

C25H21ClN4O4 (C25 H21 ClN4 O4)

Compound Name

ethyl 2-{2-[2-(3-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate

IUPAC name

ethyl 2-{2-[2-(3-chlorophenyl)-4-oxo-3H4H5H-pyrido[23-b][14]diazepin-5-yl]acetamido}benzoate

SMILES

CCOC(c(cccc1)c1NC(CN(c(nccc1)c1N=C(C1)c2cccc(Cl)c2)C1=O)=O)=O

InChI

InChI=1S/C25H21ClN4O4/c1-2-34-25(33)18-9-3-4-10-19(18)29-22(31)15-30-23(32)14-21(16-7-5-8-17(26)13-16)28-20-11-6-12-27-24(20)30/h3-13H,2,14-15H2,1H3,(H,29,31)

InChI Key

YPPQTNGXASJQEC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27249447

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.92

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.272

Distribution Coefficient, logD

4.250

Water Solubility, LogSw

-4.41

Polar Surface Area

78.126

Acid Dissociation Constant (pKa)

8.68

Base Dissociation Constant (pKb)

-1.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

L385-0892 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L385-0892 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L385-0892?
Check Price and Availability of L385-0892, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L385-0892 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L385-0892
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L385-0892
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L385-0892 available by request