L385-0893 Screening compound: methyl 2-{2-[2-(3-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate

L385-0893 Screening compound: methyl 2-{2-[2-(3-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate
L385-0893 Screening compound: methyl 2-{2-[2-(3-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L385-0893
methyl 2-{2-[2-(3-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L385-0893

Molecular Formula

C24H19ClN4O4 (C24 H19 ClN4 O4)

Compound Name

methyl 2-{2-[2-(3-chlorophenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamido}benzoate

IUPAC name

methyl 2-{2-[2-(3-chlorophenyl)-4-oxo-3H4H5H-pyrido[23-b][14]diazepin-5-yl]acetamido}benzoate

SMILES

COC(c(cccc1)c1NC(CN(c(nccc1)c1N=C(C1)c2cccc(Cl)c2)C1=O)=O)=O

InChI

InChI=1S/C24H19ClN4O4/c1-33-24(32)17-8-2-3-9-18(17)28-21(30)14-29-22(31)13-20(15-6-4-7-16(25)12-15)27-19-10-5-11-26-23(19)29/h2-12H,13-14H2,1H3,(H,28,30)

InChI Key

MYFLPLRAQAHODF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27249448

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.89

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.728

Distribution Coefficient, logD

3.706

Water Solubility, LogSw

-4.14

Polar Surface Area

78.546

Acid Dissociation Constant (pKa)

8.68

Base Dissociation Constant (pKb)

-1.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

L385-0893 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L385-0893 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L385-0893?
Check Price and Availability of L385-0893, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L385-0893 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L385-0893
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L385-0893
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L385-0893 available by request