L385-1211 Screening compound: N-(4-chloro-2-methoxy-5-methylphenyl)-2-[2-(4-ethylphenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamide

L385-1211 Screening compound: N-(4-chloro-2-methoxy-5-methylphenyl)-2-[2-(4-ethylphenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamide
L385-1211 Screening compound: N-(4-chloro-2-methoxy-5-methylphenyl)-2-[2-(4-ethylphenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L385-1211
N-(4-chloro-2-methoxy-5-methylphenyl)-2-[2-(4-ethylphenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L385-1211

Molecular Formula

C26H25ClN4O3 (C26 H25 ClN4 O3)

Compound Name

N-(4-chloro-2-methoxy-5-methylphenyl)-2-[2-(4-ethylphenyl)-4-oxo-3H,4H,5H-pyrido[2,3-b][1,4]diazepin-5-yl]acetamide

IUPAC name

N-(4-chloro-2-methoxy-5-methylphenyl)-2-[2-(4-ethylphenyl)-4-oxo-3H4H5H-pyrido[23-b][14]diazepin-5-yl]acetamide

SMILES

CCc(cc1)ccc1C(C1)=Nc2cccnc2N(CC(Nc(c(OC)c2)cc(C)c2Cl)=O)C1=O

InChI

InChI=1S/C26H25ClN4O3/c1-4-17-7-9-18(10-8-17)21-14-25(33)31(26-20(29-21)6-5-11-28-26)15-24(32)30-22-12-16(2)19(27)13-23(22)34-3/h5-13H,4,14-15H2,1-3H3,(H,30,32)

InChI Key

CJSBOTPXKMLKFF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27249518

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.96

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.248

Distribution Coefficient, logD

5.245

Water Solubility, LogSw

-5.80

Polar Surface Area

65.003

Acid Dissociation Constant (pKa)

9.53

Base Dissociation Constant (pKb)

1.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.10

L385-1211 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L385-1211 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L385-1211?
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What is the minimum amount of L385-1211 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L385-1211
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L385-1211
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L385-1211 available by request