L388-0135 Screening compound: 3-{[5-methyl-2-(3-methylphenyl)-1,3-oxazol-4-yl]methyl}[1]benzofuro[3,2-d]pyrimidin-4(3H)-one

L388-0135 Screening compound: 3-{[5-methyl-2-(3-methylphenyl)-1,3-oxazol-4-yl]methyl}[1]benzofuro[3,2-d]pyrimidin-4(3H)-one
L388-0135 Screening compound: 3-{[5-methyl-2-(3-methylphenyl)-1,3-oxazol-4-yl]methyl}[1]benzofuro[3,2-d]pyrimidin-4(3H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L388-0135
3-{[5-methyl-2-(3-methylphenyl)-1,3-oxazol-4-yl]methyl}[1]benzofuro[3,2-d]pyrimidin-4(3H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L388-0135

Molecular Formula

C22H17N3O3 (C22 H17 N3 O3)

Compound Name

3-{[5-methyl-2-(3-methylphenyl)-1,3-oxazol-4-yl]methyl}[1]benzofuro[3,2-d]pyrimidin-4(3H)-one

IUPAC name

5-{[5-methyl-2-(3-methylphenyl)-13-oxazol-4-yl]methyl}-8-oxa-35-diazatricyclo[7.4.0.0^{27}]trideca-1(13)2(7)3911-pentaen-6-one

SMILES

Cc1c(CN(C=Nc2c3oc4c2cccc4)C3=O)nc(-c2cc(C)ccc2)o1

InChI

InChI=1S/C22H17N3O3/c1-13-6-5-7-15(10-13)21-24-17(14(2)27-21)11-25-12-23-19-16-8-3-4-9-18(16)28-20(19)22(25)26/h3-10,12H,11H2,1-2H3

InChI Key

NHJWMHKRYVPJIF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27250211

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

371.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.081

Distribution Coefficient, logD

4.081

Water Solubility, LogSw

-4.39

Polar Surface Area

50.356

Acid Dissociation Constant (pKa)

28.35

Base Dissociation Constant (pKb)

-0.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

L388-0135 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L388-0135 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L388-0135?
Check Price and Availability of L388-0135, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L388-0135 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L388-0135
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L388-0135
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L388-0135 available by request