L389-0469 Screening compound: 2-{[4-(4-chlorophenyl)-7,8-dimethyl-3H-1,5-benzodiazepin-2-yl]sulfanyl}-N-phenylacetamide

L389-0469 Screening compound: 2-{[4-(4-chlorophenyl)-7,8-dimethyl-3H-1,5-benzodiazepin-2-yl]sulfanyl}-N-phenylacetamide
L389-0469 Screening compound: 2-{[4-(4-chlorophenyl)-7,8-dimethyl-3H-1,5-benzodiazepin-2-yl]sulfanyl}-N-phenylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L389-0469
2-{[4-(4-chlorophenyl)-7,8-dimethyl-3H-1,5-benzodiazepin-2-yl]sulfanyl}-N-phenylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L389-0469

Molecular Formula

C25H22ClN3OS (C25 H22 ClN3 OS)

Compound Name

2-{[4-(4-chlorophenyl)-7,8-dimethyl-3H-1,5-benzodiazepin-2-yl]sulfanyl}-N-phenylacetamide

IUPAC name

2-{[4-(4-chlorophenyl)-78-dimethyl-3H-15-benzodiazepin-2-yl]sulfanyl}-N-phenylacetamide

SMILES

Cc(c(C)c1)cc(N=C(C2)c(cc3)ccc3Cl)c1N=C2SCC(Nc1ccccc1)=O

InChI

InChI=1S/C25H22ClN3OS/c1-16-12-22-23(13-17(16)2)29-25(14-21(28-22)18-8-10-19(26)11-9-18)31-15-24(30)27-20-6-4-3-5-7-20/h3-13H,14-15H2,1-2H3,(H,27,30)

InChI Key

YXAODKZRAYATBK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27250403

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.99

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.030

Distribution Coefficient, logD

6.024

Water Solubility, LogSw

-6.12

Polar Surface Area

41.339

Acid Dissociation Constant (pKa)

12.69

Base Dissociation Constant (pKb)

5.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.00

L389-0469 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L389-0469 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L389-0469?
Check Price and Availability of L389-0469, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L389-0469 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L389-0469
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L389-0469
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L389-0469 available by request