L390-1378 Screening compound: 7-(4-ETHOXYPHENYL)-N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE

L390-1378 Screening compound: 7-(4-ETHOXYPHENYL)-N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE
L390-1378 Screening compound: 7-(4-ETHOXYPHENYL)-N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L390-1378
7-(4-ETHOXYPHENYL)-N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L390-1378

Molecular Formula

C26H25N5O3 (C26 H25 N5 O3)

Compound Name

7-(4-ETHOXYPHENYL)-N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE

IUPAC name

7-(4-ethoxyphenyl)-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]pyrazolo[15-a]pyrimidine-3-carboxamide

SMILES

CCOc(cc1)ccc1-c(n1nc2)ccnc1c2C(NCCc1c[nH]c(cc2)c1cc2OC)=O

InChI

InChI=1S/C26H25N5O3/c1-3-34-19-6-4-17(5-7-19)24-11-13-27-25-22(16-30-31(24)25)26(32)28-12-10-18-15-29-23-9-8-20(33-2)14-21(18)23/h4-9,11,13-16,29H,3,10,12H2,1-2H3,(H,28,32)

InChI Key

RYGMYVLZZXPVIB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27250560

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.169

Distribution Coefficient, logD

4.169

Water Solubility, LogSw

-4.13

Polar Surface Area

68.393

Acid Dissociation Constant (pKa)

13.17

Base Dissociation Constant (pKb)

1.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.20

L390-1378 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indole Derivatives (10091 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L390-1378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L390-1378?
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What is the minimum amount of L390-1378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L390-1378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L390-1378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L390-1378 available by request