L390-2644 Screening compound: 1-[7-(2H-1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(5-chloro-2-methylphenyl)piperazine

L390-2644 Screening compound: 1-[7-(2H-1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(5-chloro-2-methylphenyl)piperazine
L390-2644 Screening compound: 1-[7-(2H-1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(5-chloro-2-methylphenyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L390-2644
1-[7-(2H-1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(5-chloro-2-methylphenyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L390-2644

Molecular Formula

C25H22ClN5O3 (C25 H22 ClN5 O3)

Compound Name

1-[7-(2H-1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidine-3-carbonyl]-4-(5-chloro-2-methylphenyl)piperazine

IUPAC name

1-[7-(2H-13-benzodioxol-5-yl)pyrazolo[15-a]pyrimidine-3-carbonyl]-4-(5-chloro-2-methylphenyl)piperazine

SMILES

Cc(ccc(Cl)c1)c1N(CC1)CCN1C(c1c2nccc(-c(cc3)cc4c3OCO4)n2nc1)=O

InChI

InChI=1S/C25H22ClN5O3/c1-16-2-4-18(26)13-21(16)29-8-10-30(11-9-29)25(32)19-14-28-31-20(6-7-27-24(19)31)17-3-5-22-23(12-17)34-15-33-22/h2-7,12-14H,8-11,15H2,1H3

InChI Key

WIXYPTUMPUCRCK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD20736335

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.93

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.472

Distribution Coefficient, logD

4.472

Water Solubility, LogSw

-4.56

Polar Surface Area

56.323

Acid Dissociation Constant (pKa)

27.18

Base Dissociation Constant (pKb)

1.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

L390-2644 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with L390-2644 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L390-2644?
Check Price and Availability of L390-2644, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L390-2644 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L390-2644
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L390-2644
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L390-2644 available by request