L390-2659 Screening compound: 7-(2H-1,3-benzodioxol-5-yl)-N-{[4-(trifluoromethyl)phenyl]methyl}pyrazolo[1,5-a]pyrimidine-3-carboxamide

L390-2659 Screening compound: 7-(2H-1,3-benzodioxol-5-yl)-N-{[4-(trifluoromethyl)phenyl]methyl}pyrazolo[1,5-a]pyrimidine-3-carboxamide
L390-2659 Screening compound: 7-(2H-1,3-benzodioxol-5-yl)-N-{[4-(trifluoromethyl)phenyl]methyl}pyrazolo[1,5-a]pyrimidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L390-2659
7-(2H-1,3-benzodioxol-5-yl)-N-{[4-(trifluoromethyl)phenyl]methyl}pyrazolo[1,5-a]pyrimidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L390-2659

Molecular Formula

C22H15F3N4O3 (C22 H15 F3 N4 O3)

Compound Name

7-(2H-1,3-benzodioxol-5-yl)-N-{[4-(trifluoromethyl)phenyl]methyl}pyrazolo[1,5-a]pyrimidine-3-carboxamide

IUPAC name

7-(2H-13-benzodioxol-5-yl)-N-{[4-(trifluoromethyl)phenyl]methyl}pyrazolo[15-a]pyrimidine-3-carboxamide

SMILES

O=C(c1c2nccc(-c(cc3)cc4c3OCO4)n2nc1)NCc1ccc(C(F)(F)F)cc1

InChI

InChI=1S/C22H15F3N4O3/c23-22(24,25)15-4-1-13(2-5-15)10-27-21(30)16-11-28-29-17(7-8-26-20(16)29)14-3-6-18-19(9-14)32-12-31-18/h1-9,11H,10,12H2,(H,27,30)

InChI Key

FWKFCIWABILSBT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27250601

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

440.38

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.168

Distribution Coefficient, logD

4.168

Water Solubility, LogSw

-4.26

Polar Surface Area

61.129

Acid Dissociation Constant (pKa)

11.86

Base Dissociation Constant (pKb)

1.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

L390-2659 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L390-2659 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L390-2659?
Check Price and Availability of L390-2659, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L390-2659 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L390-2659
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L390-2659
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L390-2659 available by request