L391-2148 Screening compound: N-(4-fluorophenyl)-2-[4-oxo-7-(piperidin-1-yl)-3H,4H-[1,3]diazino[4,5-d]pyrimidin-3-yl]butanamide

L391-2148 Screening compound: N-(4-fluorophenyl)-2-[4-oxo-7-(piperidin-1-yl)-3H,4H-[1,3]diazino[4,5-d]pyrimidin-3-yl]butanamide
L391-2148 Screening compound: N-(4-fluorophenyl)-2-[4-oxo-7-(piperidin-1-yl)-3H,4H-[1,3]diazino[4,5-d]pyrimidin-3-yl]butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L391-2148
N-(4-fluorophenyl)-2-[4-oxo-7-(piperidin-1-yl)-3H,4H-[1,3]diazino[4,5-d]pyrimidin-3-yl]butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L391-2148

Molecular Formula

C21H23FN6O2 (C21 H23 FN6 O2)

Compound Name

N-(4-fluorophenyl)-2-[4-oxo-7-(piperidin-1-yl)-3H,4H-[1,3]diazino[4,5-d]pyrimidin-3-yl]butanamide

IUPAC name

N-(4-fluorophenyl)-2-[4-oxo-7-(piperidin-1-yl)-3H4H-[13]diazino[45-d]pyrimidin-3-yl]butanamide

SMILES

CCC(C(Nc(cc1)ccc1F)=O)N(C=Nc1c2cnc(N3CCCCC3)n1)C2=O

InChI

InChI=1S/C21H23FN6O2/c1-2-17(19(29)25-15-8-6-14(22)7-9-15)28-13-24-18-16(20(28)30)12-23-21(26-18)27-10-4-3-5-11-27/h6-9,12-13,17H,2-5,10-11H2,1H3,(H,25,29)/t17-/m0/s1

InChI Key

HJJGSVSMFWVBQS-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27250667

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.552

Distribution Coefficient, logD

2.551

Water Solubility, LogSw

-3.01

Polar Surface Area

70.841

Acid Dissociation Constant (pKa)

10.69

Base Dissociation Constant (pKb)

1.90

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.10

L391-2148 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with L391-2148 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L391-2148?
Check Price and Availability of L391-2148, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L391-2148 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L391-2148
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L391-2148
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L391-2148 available by request