L392-0245 Screening compound: 2-{7-benzyl-2-methyl-4-oxo-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-3-yl}-N-(2-ethoxyphenyl)acetamide

L392-0245 Screening compound: 2-{7-benzyl-2-methyl-4-oxo-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-3-yl}-N-(2-ethoxyphenyl)acetamide
L392-0245 Screening compound: 2-{7-benzyl-2-methyl-4-oxo-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-3-yl}-N-(2-ethoxyphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L392-0245
2-{7-benzyl-2-methyl-4-oxo-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-3-yl}-N-(2-ethoxyphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L392-0245

Molecular Formula

C25H28N4O3 (C25 H28 N4 O3)

Compound Name

2-{7-benzyl-2-methyl-4-oxo-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-3-yl}-N-(2-ethoxyphenyl)acetamide

IUPAC name

2-{7-benzyl-2-methyl-4-oxo-3H4H5H6H7H8H-pyrido[34-d]pyrimidin-3-yl}-N-(2-ethoxyphenyl)acetamide

SMILES

CCOc(cccc1)c1NC(CN(C(C)=NC1=C2CCN(Cc3ccccc3)C1)C2=O)=O

InChI

InChI=1S/C25H28N4O3/c1-3-32-23-12-8-7-11-21(23)27-24(30)17-29-18(2)26-22-16-28(14-13-20(22)25(29)31)15-19-9-5-4-6-10-19/h4-12H,3,13-17H2,1-2H3,(H,27,30)

InChI Key

JLZWSUZPDYLXGT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27250728

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.710

Distribution Coefficient, logD

2.302

Water Solubility, LogSw

-2.81

Polar Surface Area

57.492

Acid Dissociation Constant (pKa)

11.28

Base Dissociation Constant (pKb)

7.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

L392-0245 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L392-0245 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L392-0245?
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What is the minimum amount of L392-0245 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L392-0245
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L392-0245
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L392-0245 available by request