L392-1325 Screening compound: ethyl 3-{[(2,5-difluorophenyl)carbamoyl]methyl}-2-(4-methylphenyl)-4-oxo-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate

L392-1325 Screening compound: ethyl 3-{[(2,5-difluorophenyl)carbamoyl]methyl}-2-(4-methylphenyl)-4-oxo-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate
L392-1325 Screening compound: ethyl 3-{[(2,5-difluorophenyl)carbamoyl]methyl}-2-(4-methylphenyl)-4-oxo-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound L392-1325
ethyl 3-{[(2,5-difluorophenyl)carbamoyl]methyl}-2-(4-methylphenyl)-4-oxo-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L392-1325

Molecular Formula

C25H24F2N4O4 (C25 H24 F2 N4 O4)

Compound Name

ethyl 3-{[(2,5-difluorophenyl)carbamoyl]methyl}-2-(4-methylphenyl)-4-oxo-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate

IUPAC name

ethyl 3-{[(25-difluorophenyl)carbamoyl]methyl}-2-(4-methylphenyl)-4-oxo-3H4H5H6H7H8H-pyrido[34-d]pyrimidine-7-carboxylate

SMILES

CCOC(N(CC1)CC(N=C(c2ccc(C)cc2)N2CC(Nc(cc(cc3)F)c3F)=O)=C1C2=O)=O

InChI

InChI=1S/C25H24F2N4O4/c1-3-35-25(34)30-11-10-18-21(13-30)29-23(16-6-4-15(2)5-7-16)31(24(18)33)14-22(32)28-20-12-17(26)8-9-19(20)27/h4-9,12H,3,10-11,13-14H2,1-2H3,(H,28,32)

InChI Key

NPHNWAWSZUXWLM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27250774

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.619

Distribution Coefficient, logD

3.611

Water Solubility, LogSw

-3.70

Polar Surface Area

70.486

Acid Dissociation Constant (pKa)

9.17

Base Dissociation Constant (pKb)

4.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

References: we are preparing a list of scientific research reports with L392-1325 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L392-1325?
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What is the minimum amount of L392-1325 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L392-1325
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L392-1325
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L392-1325 available by request