L392-1773 Screening compound: 2-[7-benzyl-4-oxo-2-propyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-3(4H)-yl]-N-(tetrahydro-2-furanylmethyl)acetamide

L392-1773 Screening compound: 2-[7-benzyl-4-oxo-2-propyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-3(4H)-yl]-N-(tetrahydro-2-furanylmethyl)acetamide
L392-1773 Screening compound: 2-[7-benzyl-4-oxo-2-propyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-3(4H)-yl]-N-(tetrahydro-2-furanylmethyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L392-1773
2-[7-benzyl-4-oxo-2-propyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-3(4H)-yl]-N-(tetrahydro-2-furanylmethyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L392-1773

Molecular Formula

C24H32N4O3 (C24 H32 N4 O3)

Compound Name

2-[7-benzyl-4-oxo-2-propyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-3(4H)-yl]-N-(tetrahydro-2-furanylmethyl)acetamide

IUPAC name

2-{7-benzyl-4-oxo-2-propyl-3H4H5H6H7H8H-pyrido[34-d]pyrimidin-3-yl}-N-[(oxolan-2-yl)methyl]acetamide

SMILES

CCCC(N1CC(NCC2OCCC2)=O)=NC(CN(Cc2ccccc2)CC2)=C2C1=O

InChI

InChI=1S/C24H32N4O3/c1-2-7-22-26-21-16-27(15-18-8-4-3-5-9-18)12-11-20(21)24(30)28(22)17-23(29)25-14-19-10-6-13-31-19/h3-5,8-9,19H,2,6-7,10-17H2,1H3,(H,25,29)/t19-/m1/s1

InChI Key

RDUGQYJGUWXUAT-LJQANCHMSA-N

MDL Number (MFCD)

MFCD27250895

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.54

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.386

Distribution Coefficient, logD

0.426

Water Solubility, LogSw

-2.08

Polar Surface Area

62.048

Acid Dissociation Constant (pKa)

14.38

Base Dissociation Constant (pKb)

8.31

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

54.17

L392-1773 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L392-1773 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L392-1773?
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What is the minimum amount of L392-1773 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L392-1773
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L392-1773
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L392-1773 available by request