L392-1923 Screening compound: 2-[7-benzyl-4-oxo-2-(propan-2-yl)-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-3-yl]-N-[4-(trifluoromethyl)phenyl]acetamide

L392-1923 Screening compound: 2-[7-benzyl-4-oxo-2-(propan-2-yl)-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-3-yl]-N-[4-(trifluoromethyl)phenyl]acetamide
L392-1923 Screening compound: 2-[7-benzyl-4-oxo-2-(propan-2-yl)-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-3-yl]-N-[4-(trifluoromethyl)phenyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L392-1923
2-[7-benzyl-4-oxo-2-(propan-2-yl)-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-3-yl]-N-[4-(trifluoromethyl)phenyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L392-1923

Molecular Formula

C26H27F3N4O2 (C26 H27 F3 N4 O2)

Compound Name

2-[7-benzyl-4-oxo-2-(propan-2-yl)-3H,4H,5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-3-yl]-N-[4-(trifluoromethyl)phenyl]acetamide

IUPAC name

2-[7-benzyl-4-oxo-2-(propan-2-yl)-3H4H5H6H7H8H-pyrido[34-d]pyrimidin-3-yl]-N-[4-(trifluoromethyl)phenyl]acetamide

SMILES

CC(C)C(N1CC(Nc2ccc(C(F)(F)F)cc2)=O)=NC(CN(Cc2ccccc2)CC2)=C2C1=O

InChI

InChI=1S/C26H27F3N4O2/c1-17(2)24-31-22-15-32(14-18-6-4-3-5-7-18)13-12-21(22)25(35)33(24)16-23(34)30-20-10-8-19(9-11-20)26(27,28)29/h3-11,17H,12-16H2,1-2H3,(H,30,34)

InChI Key

NCGAEFMHKVOXEQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27250947

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.328

Distribution Coefficient, logD

2.692

Water Solubility, LogSw

-4.13

Polar Surface Area

52.215

Acid Dissociation Constant (pKa)

12.59

Base Dissociation Constant (pKb)

9.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

L392-1923 in Drug Discovery

Included in Screening Libraries

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with L392-1923 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L392-1923?
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What is the minimum amount of L392-1923 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L392-1923
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L392-1923
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L392-1923 available by request