L402-0025 Screening compound: N-(2-methoxyethyl)-5-methyl-7-{[(4-methylphenyl)carbamoyl]amino}-3-phenyl-1H-indole-2-carboxamide

L402-0025 Screening compound: N-(2-methoxyethyl)-5-methyl-7-{[(4-methylphenyl)carbamoyl]amino}-3-phenyl-1H-indole-2-carboxamide
L402-0025 Screening compound: N-(2-methoxyethyl)-5-methyl-7-{[(4-methylphenyl)carbamoyl]amino}-3-phenyl-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L402-0025
N-(2-methoxyethyl)-5-methyl-7-{[(4-methylphenyl)carbamoyl]amino}-3-phenyl-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L402-0025

Molecular Formula

C27H28N4O3 (C27 H28 N4 O3)

Compound Name

N-(2-methoxyethyl)-5-methyl-7-{[(4-methylphenyl)carbamoyl]amino}-3-phenyl-1H-indole-2-carboxamide

IUPAC name

N-(2-methoxyethyl)-5-methyl-7-{[(4-methylphenyl)carbamoyl]amino}-3-phenyl-1H-indole-2-carboxamide

SMILES

Cc(cc1)ccc1NC(Nc(cc(C)cc12)c1[nH]c(C(NCCOC)=O)c2-c1ccccc1)=O

InChI

InChI=1S/C27H28N4O3/c1-17-9-11-20(12-10-17)29-27(33)30-22-16-18(2)15-21-23(19-7-5-4-6-8-19)25(31-24(21)22)26(32)28-13-14-34-3/h4-12,15-16,31H,13-14H2,1-3H3,(H,28,32)(H2,29,30,33)

InChI Key

YFUKQHMAJQOWFB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15126024

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.54

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

4.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.235

Distribution Coefficient, logD

5.235

Water Solubility, LogSw

-5.16

Polar Surface Area

75.331

Acid Dissociation Constant (pKa)

12.76

Base Dissociation Constant (pKb)

0.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

L402-0025 in Drug Discovery

Included in Screening Libraries

ACE2 Library (3043 compounds)

Anticancer Library (62698 compounds)

CORONAVIRUS Library (20774 compounds)

Indole Derivatives (10091 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Cancer
Structure:
  • Cyclic compounds
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L402-0025 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L402-0025?
Check Price and Availability of L402-0025, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L402-0025 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L402-0025
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L402-0025
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L402-0025 available by request