L409-0154 Screening compound: 3-[1-(2,3-dihydro-1H-indol-1-yl)-1-oxopropan-2-yl]-1-(2,4-dimethoxyphenyl)urea

L409-0154 Screening compound: 3-[1-(2,3-dihydro-1H-indol-1-yl)-1-oxopropan-2-yl]-1-(2,4-dimethoxyphenyl)urea
L409-0154 Screening compound: 3-[1-(2,3-dihydro-1H-indol-1-yl)-1-oxopropan-2-yl]-1-(2,4-dimethoxyphenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L409-0154
3-[1-(2,3-dihydro-1H-indol-1-yl)-1-oxopropan-2-yl]-1-(2,4-dimethoxyphenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L409-0154

Molecular Formula

C20H23N3O4 (C20 H23 N3 O4)

Compound Name

3-[1-(2,3-dihydro-1H-indol-1-yl)-1-oxopropan-2-yl]-1-(2,4-dimethoxyphenyl)urea

IUPAC name

3-[1-(23-dihydro-1H-indol-1-yl)-1-oxopropan-2-yl]-1-(24-dimethoxyphenyl)urea

SMILES

CC(C(N(CC1)c2c1cccc2)=O)NC(Nc(ccc(OC)c1)c1OC)=O

InChI

InChI=1S/C20H23N3O4/c1-13(19(24)23-11-10-14-6-4-5-7-17(14)23)21-20(25)22-16-9-8-15(26-2)12-18(16)27-3/h4-9,12-13H,10-11H2,1-3H3,(H2,21,22,25)/t13-/m0/s1

InChI Key

HZFDUWIPYRJPJO-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD15126305

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

369.42

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.455

Distribution Coefficient, logD

2.455

Water Solubility, LogSw

-3.06

Polar Surface Area

63.453

Acid Dissociation Constant (pKa)

12.51

Base Dissociation Constant (pKb)

2.45

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.00

L409-0154 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L409-0154 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L409-0154?
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What is the minimum amount of L409-0154 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L409-0154
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L409-0154
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L409-0154 available by request