L409-0165 Screening compound: 1-(2,4-difluorophenyl)-3-[1-(2,3-dihydro-1H-indol-1-yl)-1-oxopropan-2-yl]urea

L409-0165 Screening compound: 1-(2,4-difluorophenyl)-3-[1-(2,3-dihydro-1H-indol-1-yl)-1-oxopropan-2-yl]urea
L409-0165 Screening compound: 1-(2,4-difluorophenyl)-3-[1-(2,3-dihydro-1H-indol-1-yl)-1-oxopropan-2-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L409-0165
1-(2,4-difluorophenyl)-3-[1-(2,3-dihydro-1H-indol-1-yl)-1-oxopropan-2-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L409-0165

Molecular Formula

C18H17F2N3O2 (C18 H17 F2 N3 O2)

Compound Name

1-(2,4-difluorophenyl)-3-[1-(2,3-dihydro-1H-indol-1-yl)-1-oxopropan-2-yl]urea

IUPAC name

1-(24-difluorophenyl)-3-[1-(23-dihydro-1H-indol-1-yl)-1-oxopropan-2-yl]urea

SMILES

CC(C(N(CC1)c2c1cccc2)=O)NC(Nc(ccc(F)c1)c1F)=O

InChI

InChI=1S/C18H17F2N3O2/c1-11(17(24)23-9-8-12-4-2-3-5-16(12)23)21-18(25)22-15-7-6-13(19)10-14(15)20/h2-7,10-11H,8-9H2,1H3,(H2,21,22,25)/t11-/m0/s1

InChI Key

VVWSKYAGGUIZRJ-NSHDSACASA-N

MDL Number (MFCD)

MFCD15126314

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

345.35

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.625

Distribution Coefficient, logD

2.625

Water Solubility, LogSw

-3.22

Polar Surface Area

48.279

Acid Dissociation Constant (pKa)

10.60

Base Dissociation Constant (pKb)

2.53

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.20

L409-0165 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Mechanism of action:
  • Epigenetic
  • Epigenetic
Targets:
  • Others

References: we are preparing a list of scientific research reports with L409-0165 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L409-0165?
Check Price and Availability of L409-0165, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L409-0165 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L409-0165
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L409-0165
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L409-0165 available by request