L413-0236 Screening compound: 2-methyl-1-{5-[4-(4-methylpiperidine-1-carbonyl)phenyl]-2,3-dihydro-1H-indol-1-yl}propan-1-one

L413-0236 Screening compound: 2-methyl-1-{5-[4-(4-methylpiperidine-1-carbonyl)phenyl]-2,3-dihydro-1H-indol-1-yl}propan-1-one
L413-0236 Screening compound: 2-methyl-1-{5-[4-(4-methylpiperidine-1-carbonyl)phenyl]-2,3-dihydro-1H-indol-1-yl}propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L413-0236
2-methyl-1-{5-[4-(4-methylpiperidine-1-carbonyl)phenyl]-2,3-dihydro-1H-indol-1-yl}propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L413-0236

Molecular Formula

C25H30N2O2 (C25 H30 N2 O2)

Compound Name

2-methyl-1-{5-[4-(4-methylpiperidine-1-carbonyl)phenyl]-2,3-dihydro-1H-indol-1-yl}propan-1-one

IUPAC name

2-methyl-1-{5-[4-(4-methylpiperidine-1-carbonyl)phenyl]-23-dihydro-1H-indol-1-yl}propan-1-one

SMILES

CC(C)C(N(CC1)c(cc2)c1cc2-c(cc1)ccc1C(N1CCC(C)CC1)=O)=O

InChI

InChI=1S/C25H30N2O2/c1-17(2)24(28)27-15-12-22-16-21(8-9-23(22)27)19-4-6-20(7-5-19)25(29)26-13-10-18(3)11-14-26/h4-9,16-18H,10-15H2,1-3H3

InChI Key

DDPJBAJGLARGOB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27251452

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

390.53

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.705

Distribution Coefficient, logD

4.705

Water Solubility, LogSw

-4.47

Polar Surface Area

32.566

Acid Dissociation Constant (pKa)

21.07

Base Dissociation Constant (pKb)

-0.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

L413-0236 in Drug Discovery

Included in Screening Libraries

Bromodomain Modulators Library (5801 compounds)

Lipid Metabolism Library (9174 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Metabolic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L413-0236 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L413-0236?
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What is the minimum amount of L413-0236 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L413-0236
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L413-0236
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L413-0236 available by request