L418-0119 Screening compound: N-(3-fluoro-4-methylphenyl)-5-[4-(morpholine-4-carbonyl)phenyl]-2,3-dihydro-1H-indole-1-carboxamide
Chemical Structure Depiction of ChemDiv screening compound L418-0119
N-(3-fluoro-4-methylphenyl)-5-[4-(morpholine-4-carbonyl)phenyl]-2,3-dihydro-1H-indole-1-carboxamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
L418-0119
Molecular Formula
C27H26FN3O3 (C27 H26 FN3 O3)
Compound Name
N-(3-fluoro-4-methylphenyl)-5-[4-(morpholine-4-carbonyl)phenyl]-2,3-dihydro-1H-indole-1-carboxamide
IUPAC name
N-(3-fluoro-4-methylphenyl)-5-[4-(morpholine-4-carbonyl)phenyl]-23-dihydro-1H-indole-1-carboxamide
SMILES
Cc(ccc(NC(N(CC1)c(cc2)c1cc2-c(cc1)ccc1C(N1CCOCC1)=O)=O)c1)c1F
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
459.52
Hydrogen Bond Acceptors Count
5.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
6.00
Number of Nitrogen and Oxygen Atoms
6
Partition Coefficient, logP
4.757
Distribution Coefficient, logD
4.757
Water Solubility, LogSw
-4.48
Polar Surface Area
49.023
Acid Dissociation Constant (pKa)
11.02
Base Dissociation Constant (pKb)
-1.22
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
25.90
L418-0119 in Drug Discovery
Included in Screening Libraries
Bromodomain Modulators Library (5801 compounds)
Lipid Metabolism Library (9174 compounds)
MDM2-p53 interaction inhibitors Library (21687 compounds)
Included in 1.7M Stock Database
- Cardiovascular
- Metabolic
- Cancer
- PPI modulators
References: we are preparing a list of scientific research reports with L418-0119 chemical compound. It will be published here after verification.
Frequently Asked Questions
Check Price and Availability of L418-0119, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)