L418-0123 Screening compound: N-(2,5-difluorophenyl)-5-[4-(morpholine-4-carbonyl)phenyl]-2,3-dihydro-1H-indole-1-carboxamide

L418-0123 Screening compound: N-(2,5-difluorophenyl)-5-[4-(morpholine-4-carbonyl)phenyl]-2,3-dihydro-1H-indole-1-carboxamide
L418-0123 Screening compound: N-(2,5-difluorophenyl)-5-[4-(morpholine-4-carbonyl)phenyl]-2,3-dihydro-1H-indole-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L418-0123
N-(2,5-difluorophenyl)-5-[4-(morpholine-4-carbonyl)phenyl]-2,3-dihydro-1H-indole-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L418-0123

Molecular Formula

C26H23F2N3O3 (C26 H23 F2 N3 O3)

Compound Name

N-(2,5-difluorophenyl)-5-[4-(morpholine-4-carbonyl)phenyl]-2,3-dihydro-1H-indole-1-carboxamide

IUPAC name

N-(25-difluorophenyl)-5-[4-(morpholine-4-carbonyl)phenyl]-23-dihydro-1H-indole-1-carboxamide

SMILES

O=C(c(cc1)ccc1-c(cc1)cc(CC2)c1N2C(Nc(cc(cc1)F)c1F)=O)N1CCOCC1

InChI

InChI=1S/C26H23F2N3O3/c27-21-6-7-22(28)23(16-21)29-26(33)31-10-9-20-15-19(5-8-24(20)31)17-1-3-18(4-2-17)25(32)30-11-13-34-14-12-30/h1-8,15-16H,9-14H2,(H,29,33)

InChI Key

UQGRHNSANICBHM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15126833

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.671

Distribution Coefficient, logD

4.665

Water Solubility, LogSw

-4.68

Polar Surface Area

48.326

Acid Dissociation Constant (pKa)

9.26

Base Dissociation Constant (pKb)

-2.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.10

L418-0123 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Bromodomain Modulators Library (5801 compounds)

Cardiovascular Library (22201 compounds)

Lipid Metabolism Library (9174 compounds)

Protein-Protein Interaction Library (218420 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Cardiovascular
  • Metabolic
Mechanism of action:
  • PPI modulators
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L418-0123 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L418-0123?
Check Price and Availability of L418-0123, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L418-0123 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L418-0123
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L418-0123
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L418-0123 available by request