L423-0944 Screening compound: N-[(2,4-difluorophenyl)methyl]-1-(4-acetamidophenyl)cyclohexane-1-carboxamide

L423-0944 Screening compound: N-[(2,4-difluorophenyl)methyl]-1-(4-acetamidophenyl)cyclohexane-1-carboxamide
L423-0944 Screening compound: N-[(2,4-difluorophenyl)methyl]-1-(4-acetamidophenyl)cyclohexane-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L423-0944
N-[(2,4-difluorophenyl)methyl]-1-(4-acetamidophenyl)cyclohexane-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L423-0944

Molecular Formula

C22H24F2N2O2 (C22 H24 F2 N2 O2)

Compound Name

N-[(2,4-difluorophenyl)methyl]-1-(4-acetamidophenyl)cyclohexane-1-carboxamide

IUPAC name

N-[(24-difluorophenyl)methyl]-1-(4-acetamidophenyl)cyclohexane-1-carboxamide

SMILES

CC(Nc1ccc(C2(CCCCC2)C(NCc(ccc(F)c2)c2F)=O)cc1)=O

InChI

InChI=1S/C22H24F2N2O2/c1-15(27)26-19-9-6-17(7-10-19)22(11-3-2-4-12-22)21(28)25-14-16-5-8-18(23)13-20(16)24/h5-10,13H,2-4,11-12,14H2,1H3,(H,25,28)(H,26,27)

InChI Key

BLBZTENVMFKGFD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27251889

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.074

Distribution Coefficient, logD

4.074

Water Solubility, LogSw

-4.13

Polar Surface Area

47.834

Acid Dissociation Constant (pKa)

11.27

Base Dissociation Constant (pKb)

0.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

L423-0944 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L423-0944 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L423-0944?
Check Price and Availability of L423-0944, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L423-0944 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L423-0944
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L423-0944
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L423-0944 available by request