L424-1293 Screening compound: 1-{4-[(methylsulfonyl)amino]phenyl}-N~1~-(2-pyridylmethyl)-1-cyclohexanecarboxamide

L424-1293 Screening compound: 1-{4-[(methylsulfonyl)amino]phenyl}-N~1~-(2-pyridylmethyl)-1-cyclohexanecarboxamide
L424-1293 Screening compound: 1-{4-[(methylsulfonyl)amino]phenyl}-N~1~-(2-pyridylmethyl)-1-cyclohexanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L424-1293
1-{4-[(methylsulfonyl)amino]phenyl}-N~1~-(2-pyridylmethyl)-1-cyclohexanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L424-1293

Molecular Formula

C20H25N3O3S (C20 H25 N3 O3 S)

Compound Name

1-{4-[(methylsulfonyl)amino]phenyl}-N~1~-(2-pyridylmethyl)-1-cyclohexanecarboxamide

IUPAC name

n/a

SMILES

CS(Nc1ccc(C2(CCCCC2)C(NCc2ncccc2)=O)cc1)(=O)=O

InChI

InChI=1S/C20H25N3O3S/c1-27(25,26)23-17-10-8-16(9-11-17)20(12-4-2-5-13-20)19(24)22-15-18-7-3-6-14-21-18/h3,6-11,14,23H,2,4-5,12-13,15H2,1H3,(H,22,24)

InChI Key

GUEMHNMYRLWNDF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27251996

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.488

Distribution Coefficient, logD

2.485

Water Solubility, LogSw

-2.76

Polar Surface Area

75.983

Acid Dissociation Constant (pKa)

9.58

Base Dissociation Constant (pKb)

3.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

L424-1293 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L424-1293 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L424-1293?
Check Price and Availability of L424-1293, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L424-1293 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L424-1293
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L424-1293
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L424-1293 available by request