L426-2864 Screening compound: N-(4-{1-[4-(4-methoxyphenyl)piperazine-1-carbonyl]cyclobutyl}phenyl)cyclopropanecarboxamide

L426-2864 Screening compound: N-(4-{1-[4-(4-methoxyphenyl)piperazine-1-carbonyl]cyclobutyl}phenyl)cyclopropanecarboxamide
L426-2864 Screening compound: N-(4-{1-[4-(4-methoxyphenyl)piperazine-1-carbonyl]cyclobutyl}phenyl)cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L426-2864
N-(4-{1-[4-(4-methoxyphenyl)piperazine-1-carbonyl]cyclobutyl}phenyl)cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L426-2864

Molecular Formula

C26H31N3O3 (C26 H31 N3 O3)

Compound Name

N-(4-{1-[4-(4-methoxyphenyl)piperazine-1-carbonyl]cyclobutyl}phenyl)cyclopropanecarboxamide

IUPAC name

N-(4-{1-[4-(4-methoxyphenyl)piperazine-1-carbonyl]cyclobutyl}phenyl)cyclopropanecarboxamide

SMILES

COc(cc1)ccc1N(CC1)CCN1C(C1(CCC1)c(cc1)ccc1NC(C1CC1)=O)=O

InChI

InChI=1S/C26H31N3O3/c1-32-23-11-9-22(10-12-23)28-15-17-29(18-16-28)25(31)26(13-2-14-26)20-5-7-21(8-6-20)27-24(30)19-3-4-19/h5-12,19H,2-4,13-18H2,1H3,(H,27,30)

InChI Key

WYTVJFAVMKAPIJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27252166

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.55

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.867

Distribution Coefficient, logD

3.867

Water Solubility, LogSw

-4.03

Polar Surface Area

51.557

Acid Dissociation Constant (pKa)

12.86

Base Dissociation Constant (pKb)

4.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.20

L426-2864 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L426-2864 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L426-2864?
Check Price and Availability of L426-2864, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L426-2864 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L426-2864
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L426-2864
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L426-2864 available by request