L426-2948 Screening compound: N-(4-chloro-2-fluorophenyl)-1-(4-{[(methylamino)carbonyl]amino}phenyl)-1-cyclobutanecarboxamide

L426-2948 Screening compound: N-(4-chloro-2-fluorophenyl)-1-(4-{[(methylamino)carbonyl]amino}phenyl)-1-cyclobutanecarboxamide
L426-2948 Screening compound: N-(4-chloro-2-fluorophenyl)-1-(4-{[(methylamino)carbonyl]amino}phenyl)-1-cyclobutanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L426-2948
N-(4-chloro-2-fluorophenyl)-1-(4-{[(methylamino)carbonyl]amino}phenyl)-1-cyclobutanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L426-2948

Molecular Formula

C19H19ClFN3O2 (C19 H19 ClFN3 O2)

Compound Name

N-(4-chloro-2-fluorophenyl)-1-(4-{[(methylamino)carbonyl]amino}phenyl)-1-cyclobutanecarboxamide

IUPAC name

n/a

SMILES

CNC(Nc1ccc(C2(CCC2)C(Nc(ccc(Cl)c2)c2F)=O)cc1)=O

InChI

InChI=1S/C19H19ClFN3O2/c1-22-18(26)23-14-6-3-12(4-7-14)19(9-2-10-19)17(25)24-16-8-5-13(20)11-15(16)21/h3-8,11H,2,9-10H2,1H3,(H,24,25)(H2,22,23,26)

InChI Key

FRQASSYXQMVXLY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27641431

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.83

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.062

Distribution Coefficient, logD

3.890

Water Solubility, LogSw

-4.45

Polar Surface Area

56.931

Acid Dissociation Constant (pKa)

7.71

Base Dissociation Constant (pKb)

0.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.32

L426-2948 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L426-2948 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L426-2948?
Check Price and Availability of L426-2948, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L426-2948 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L426-2948
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L426-2948
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L426-2948 available by request