L428-0377 Screening compound: 5-(4-methylphenyl)-N-[1-(4-methylphenyl)ethyl]pyridine-3-carboxamide

L428-0377 Screening compound: 5-(4-methylphenyl)-N-[1-(4-methylphenyl)ethyl]pyridine-3-carboxamide
L428-0377 Screening compound: 5-(4-methylphenyl)-N-[1-(4-methylphenyl)ethyl]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L428-0377
5-(4-methylphenyl)-N-[1-(4-methylphenyl)ethyl]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L428-0377

Molecular Formula

C22H22N2O (C22 H22 N2 O)

Compound Name

5-(4-methylphenyl)-N-[1-(4-methylphenyl)ethyl]pyridine-3-carboxamide

IUPAC name

5-(4-methylphenyl)-N-[1-(4-methylphenyl)ethyl]pyridine-3-carboxamide

SMILES

CC(c1ccc(C)cc1)NC(c1cncc(-c2ccc(C)cc2)c1)=O

InChI

InChI=1S/C22H22N2O/c1-15-4-8-18(9-5-15)17(3)24-22(25)21-12-20(13-23-14-21)19-10-6-16(2)7-11-19/h4-14,17H,1-3H3,(H,24,25)/t17-/m0/s1

InChI Key

GRSRMLMUNITIBN-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27252264

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

330.43

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

4.577

Distribution Coefficient, logD

4.577

Water Solubility, LogSw

-4.26

Polar Surface Area

33.151

Acid Dissociation Constant (pKa)

11.83

Base Dissociation Constant (pKb)

3.20

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

18.18

L428-0377 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Glucocorticoid receptors Library (4806 compounds)

Targeted Diversity Library (40567 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Nervous system
Agro:
  • Agro
Targets:
  • Nuclear receptors
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L428-0377 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L428-0377?
Check Price and Availability of L428-0377, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L428-0377 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L428-0377
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L428-0377
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L428-0377 available by request