L428-0793 Screening compound: 5-(4-methoxyphenyl)-N~3~-(4-morpholinophenyl)nicotinamide

L428-0793 Screening compound: 5-(4-methoxyphenyl)-N~3~-(4-morpholinophenyl)nicotinamide
L428-0793 Screening compound: 5-(4-methoxyphenyl)-N~3~-(4-morpholinophenyl)nicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L428-0793
5-(4-methoxyphenyl)-N~3~-(4-morpholinophenyl)nicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L428-0793

Molecular Formula

C23H23N3O3 (C23 H23 N3 O3)

Compound Name

5-(4-methoxyphenyl)-N~3~-(4-morpholinophenyl)nicotinamide

IUPAC name

n/a

SMILES

COc(cc1)ccc1-c1cc(C(Nc(cc2)ccc2N2CCOCC2)=O)cnc1

InChI

InChI=1S/C23H23N3O3/c1-28-22-8-2-17(3-9-22)18-14-19(16-24-15-18)23(27)25-20-4-6-21(7-5-20)26-10-12-29-13-11-26/h2-9,14-16H,10-13H2,1H3,(H,25,27)

InChI Key

NPDWLCZEJMTRCQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27252294

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.511

Distribution Coefficient, logD

3.510

Water Solubility, LogSw

-3.61

Polar Surface Area

51.570

Acid Dissociation Constant (pKa)

11.19

Base Dissociation Constant (pKb)

6.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

L428-0793 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Anti-infective Library (19449 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Immune system
  • animal
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L428-0793 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L428-0793?
Check Price and Availability of L428-0793, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L428-0793 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L428-0793
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L428-0793
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L428-0793 available by request