L428-0846 Screening compound: 5-(4-METHOXYPHENYL)-N-[(4-METHOXYPHENYL)METHYL]PYRIDINE-3-CARBOXAMIDE

L428-0846 Screening compound: 5-(4-METHOXYPHENYL)-N-[(4-METHOXYPHENYL)METHYL]PYRIDINE-3-CARBOXAMIDE
L428-0846 Screening compound: 5-(4-METHOXYPHENYL)-N-[(4-METHOXYPHENYL)METHYL]PYRIDINE-3-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L428-0846
5-(4-METHOXYPHENYL)-N-[(4-METHOXYPHENYL)METHYL]PYRIDINE-3-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L428-0846

Molecular Formula

C21H20N2O3 (C21 H20 N2 O3)

Compound Name

5-(4-METHOXYPHENYL)-N-[(4-METHOXYPHENYL)METHYL]PYRIDINE-3-CARBOXAMIDE

IUPAC name

5-(4-methoxyphenyl)-N-[(4-methoxyphenyl)methyl]pyridine-3-carboxamide

SMILES

COc1ccc(CNC(c2cncc(-c(cc3)ccc3OC)c2)=O)cc1

InChI

InChI=1S/C21H20N2O3/c1-25-19-7-3-15(4-8-19)12-23-21(24)18-11-17(13-22-14-18)16-5-9-20(26-2)10-6-16/h3-11,13-14H,12H2,1-2H3,(H,23,24)

InChI Key

BROLQAQGCYVZQI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27252322

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

348.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.440

Distribution Coefficient, logD

3.440

Water Solubility, LogSw

-3.55

Polar Surface Area

49.075

Acid Dissociation Constant (pKa)

12.86

Base Dissociation Constant (pKb)

3.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.29

L428-0846 in Drug Discovery

Included in Screening Libraries

Antiviral HBV Library (10007 compounds)

C-Met Library (15277 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with L428-0846 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L428-0846?
Check Price and Availability of L428-0846, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L428-0846 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L428-0846
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L428-0846
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L428-0846 available by request