L429-0373 Screening compound: 6-(3-morpholino-3-oxopropyl)-3-phenylisoxazolo[4,5-d]pyrimidin-7(6H)-one

L429-0373 Screening compound: 6-(3-morpholino-3-oxopropyl)-3-phenylisoxazolo[4,5-d]pyrimidin-7(6H)-one
L429-0373 Screening compound: 6-(3-morpholino-3-oxopropyl)-3-phenylisoxazolo[4,5-d]pyrimidin-7(6H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L429-0373
6-(3-morpholino-3-oxopropyl)-3-phenylisoxazolo[4,5-d]pyrimidin-7(6H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L429-0373

Molecular Formula

C18H18N4O4 (C18 H18 N4 O4)

Compound Name

6-(3-morpholino-3-oxopropyl)-3-phenylisoxazolo[4,5-d]pyrimidin-7(6H)-one

IUPAC name

6-[3-(morpholin-4-yl)-3-oxopropyl]-3-phenyl-6H7H-[12]oxazolo[45-d]pyrimidin-7-one

SMILES

O=C(CCN(C=Nc1c2onc1-c1ccccc1)C2=O)N1CCOCC1

InChI

InChI=1S/C18H18N4O4/c23-14(21-8-10-25-11-9-21)6-7-22-12-19-16-15(13-4-2-1-3-5-13)20-26-17(16)18(22)24/h1-5,12H,6-11H2

InChI Key

LWTLGMRCJVHCAV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27252407

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

354.37

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.401

Distribution Coefficient, logD

0.401

Water Solubility, LogSw

-1.41

Polar Surface Area

70.527

Acid Dissociation Constant (pKa)

24.02

Base Dissociation Constant (pKb)

0.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.33

L429-0373 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with L429-0373 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L429-0373?
Check Price and Availability of L429-0373, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L429-0373 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L429-0373
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L429-0373
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L429-0373 available by request