L429-0786 Screening compound: 3-[3-(4-ethylphenyl)-7-oxo-6H,7H-[1,2]oxazolo[4,5-d]pyrimidin-6-yl]-N-(1-phenylethyl)propanamide

L429-0786 Screening compound: 3-[3-(4-ethylphenyl)-7-oxo-6H,7H-[1,2]oxazolo[4,5-d]pyrimidin-6-yl]-N-(1-phenylethyl)propanamide
L429-0786 Screening compound: 3-[3-(4-ethylphenyl)-7-oxo-6H,7H-[1,2]oxazolo[4,5-d]pyrimidin-6-yl]-N-(1-phenylethyl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L429-0786
3-[3-(4-ethylphenyl)-7-oxo-6H,7H-[1,2]oxazolo[4,5-d]pyrimidin-6-yl]-N-(1-phenylethyl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L429-0786

Molecular Formula

C24H24N4O3 (C24 H24 N4 O3)

Compound Name

3-[3-(4-ethylphenyl)-7-oxo-6H,7H-[1,2]oxazolo[4,5-d]pyrimidin-6-yl]-N-(1-phenylethyl)propanamide

IUPAC name

3-[3-(4-ethylphenyl)-7-oxo-6H7H-[12]oxazolo[45-d]pyrimidin-6-yl]-N-(1-phenylethyl)propanamide

SMILES

CCc(cc1)ccc1-c1noc2c1N=CN(CCC(NC(C)c1ccccc1)=O)C2=O

InChI

InChI=1S/C24H24N4O3/c1-3-17-9-11-19(12-10-17)21-22-23(31-27-21)24(30)28(15-25-22)14-13-20(29)26-16(2)18-7-5-4-6-8-18/h4-12,15-16H,3,13-14H2,1-2H3,(H,26,29)/t16-/m0/s1

InChI Key

LHUXDSQOJZNGBW-INIZCTEOSA-N

MDL Number (MFCD)

MFCD28119852

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.507

Distribution Coefficient, logD

3.507

Water Solubility, LogSw

-3.55

Polar Surface Area

69.860

Acid Dissociation Constant (pKa)

12.65

Base Dissociation Constant (pKb)

0.43

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

L429-0786 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MCL1 Targeted Library (12200 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with L429-0786 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L429-0786?
Check Price and Availability of L429-0786, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L429-0786 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L429-0786
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L429-0786
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L429-0786 available by request