L438-0136 Screening compound: ethyl 2-[4-({[8-fluoro-2-(piperidin-1-yl)quinolin-6-yl]carbamoyl}amino)phenyl]acetate

L438-0136 Screening compound: ethyl 2-[4-({[8-fluoro-2-(piperidin-1-yl)quinolin-6-yl]carbamoyl}amino)phenyl]acetate
L438-0136 Screening compound: ethyl 2-[4-({[8-fluoro-2-(piperidin-1-yl)quinolin-6-yl]carbamoyl}amino)phenyl]acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound L438-0136
ethyl 2-[4-({[8-fluoro-2-(piperidin-1-yl)quinolin-6-yl]carbamoyl}amino)phenyl]acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L438-0136

Molecular Formula

C25H27FN4O3 (C25 H27 FN4 O3)

Compound Name

ethyl 2-[4-({[8-fluoro-2-(piperidin-1-yl)quinolin-6-yl]carbamoyl}amino)phenyl]acetate

IUPAC name

ethyl 2-[4-({[8-fluoro-2-(piperidin-1-yl)quinolin-6-yl]carbamoyl}amino)phenyl]acetate

SMILES

CCOC(Cc(cc1)ccc1NC(Nc1cc2ccc(N3CCCCC3)nc2c(F)c1)=O)=O

InChI

InChI=1S/C25H27FN4O3/c1-2-33-23(31)14-17-6-9-19(10-7-17)27-25(32)28-20-15-18-8-11-22(29-24(18)21(26)16-20)30-12-4-3-5-13-30/h6-11,15-16H,2-5,12-14H2,1H3,(H2,27,28,32)

InChI Key

CRIQAXGDNDMDLI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27252702

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.782

Distribution Coefficient, logD

5.781

Water Solubility, LogSw

-5.69

Polar Surface Area

64.717

Acid Dissociation Constant (pKa)

11.87

Base Dissociation Constant (pKb)

3.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

L438-0136 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L438-0136 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L438-0136?
Check Price and Availability of L438-0136, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L438-0136 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L438-0136
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L438-0136
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L438-0136 available by request