L438-0147 Screening compound: 3-cyclopentyl-1-[8-fluoro-2-(piperidin-1-yl)quinolin-6-yl]urea

L438-0147 Screening compound: 3-cyclopentyl-1-[8-fluoro-2-(piperidin-1-yl)quinolin-6-yl]urea
L438-0147 Screening compound: 3-cyclopentyl-1-[8-fluoro-2-(piperidin-1-yl)quinolin-6-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L438-0147
3-cyclopentyl-1-[8-fluoro-2-(piperidin-1-yl)quinolin-6-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L438-0147

Molecular Formula

C20H25FN4O (C20 H25 FN4 O)

Compound Name

3-cyclopentyl-1-[8-fluoro-2-(piperidin-1-yl)quinolin-6-yl]urea

IUPAC name

3-cyclopentyl-1-[8-fluoro-2-(piperidin-1-yl)quinolin-6-yl]urea

SMILES

O=C(NC1CCCC1)Nc1cc2ccc(N3CCCCC3)nc2c(F)c1

InChI

InChI=1S/C20H25FN4O/c21-17-13-16(23-20(26)22-15-6-2-3-7-15)12-14-8-9-18(24-19(14)17)25-10-4-1-5-11-25/h8-9,12-13,15H,1-7,10-11H2,(H2,22,23,26)

InChI Key

SESKQQDTHFGYND-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27252707

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.44

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.883

Distribution Coefficient, logD

4.883

Water Solubility, LogSw

-5.00

Polar Surface Area

45.972

Acid Dissociation Constant (pKa)

12.51

Base Dissociation Constant (pKb)

3.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L438-0147 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

3D-Pharmacophore Based Diversity Library (49813 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with L438-0147 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L438-0147?
Check Price and Availability of L438-0147, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L438-0147 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L438-0147
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L438-0147
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L438-0147 available by request