L438-0213 Screening compound: 1-(5-chloro-2-methoxyphenyl)-3-[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]urea

L438-0213 Screening compound: 1-(5-chloro-2-methoxyphenyl)-3-[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]urea
L438-0213 Screening compound: 1-(5-chloro-2-methoxyphenyl)-3-[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L438-0213
1-(5-chloro-2-methoxyphenyl)-3-[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L438-0213

Molecular Formula

C21H20ClFN4O3 (C21 H20 ClFN4 O3)

Compound Name

1-(5-chloro-2-methoxyphenyl)-3-[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]urea

IUPAC name

1-(5-chloro-2-methoxyphenyl)-3-[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]urea

SMILES

COc(ccc(Cl)c1)c1NC(Nc1cc2ccc(N3CCOCC3)nc2c(F)c1)=O

InChI

InChI=1S/C21H20ClFN4O3/c1-29-18-4-3-14(22)11-17(18)25-21(28)24-15-10-13-2-5-19(26-20(13)16(23)12-15)27-6-8-30-9-7-27/h2-5,10-12H,6-9H2,1H3,(H2,24,25,28)

InChI Key

CNFASQGIIHPDRP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27252738

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.87

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.822

Distribution Coefficient, logD

4.814

Water Solubility, LogSw

-4.94

Polar Surface Area

59.400

Acid Dissociation Constant (pKa)

9.16

Base Dissociation Constant (pKb)

3.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

L438-0213 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds

References: we are preparing a list of scientific research reports with L438-0213 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L438-0213?
Check Price and Availability of L438-0213, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L438-0213 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L438-0213
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L438-0213
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L438-0213 available by request