L438-0244 Screening compound: ethyl 3-({[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]carbamoyl}amino)-3-phenylpropanoate

L438-0244 Screening compound: ethyl 3-({[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]carbamoyl}amino)-3-phenylpropanoate
L438-0244 Screening compound: ethyl 3-({[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]carbamoyl}amino)-3-phenylpropanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L438-0244
ethyl 3-({[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]carbamoyl}amino)-3-phenylpropanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L438-0244

Molecular Formula

C25H27FN4O4 (C25 H27 FN4 O4)

Compound Name

ethyl 3-({[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]carbamoyl}amino)-3-phenylpropanoate

IUPAC name

ethyl 3-({[8-fluoro-2-(morpholin-4-yl)quinolin-6-yl]carbamoyl}amino)-3-phenylpropanoate

SMILES

CCOC(CC(c1ccccc1)NC(Nc1cc2ccc(N3CCOCC3)nc2c(F)c1)=O)=O

InChI

InChI=1S/C25H27FN4O4/c1-2-34-23(31)16-21(17-6-4-3-5-7-17)28-25(32)27-19-14-18-8-9-22(29-24(18)20(26)15-19)30-10-12-33-13-11-30/h3-9,14-15,21H,2,10-13,16H2,1H3,(H2,27,28,32)/t21-/m0/s1

InChI Key

JGTVNUNOZSAHPB-NRFANRHFSA-N

MDL Number (MFCD)

MFCD27252752

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.314

Distribution Coefficient, logD

4.314

Water Solubility, LogSw

-4.24

Polar Surface Area

73.578

Acid Dissociation Constant (pKa)

12.65

Base Dissociation Constant (pKb)

3.94

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

32.00

L438-0244 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • Phosphatases

References: we are preparing a list of scientific research reports with L438-0244 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L438-0244?
Check Price and Availability of L438-0244, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L438-0244 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L438-0244
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L438-0244
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L438-0244 available by request