L444-0258 Screening compound: N-(2-methylpropyl)-1-[4-(4-propylbenzenesulfonamido)benzoyl]piperidine-3-carboxamide

L444-0258 Screening compound: N-(2-methylpropyl)-1-[4-(4-propylbenzenesulfonamido)benzoyl]piperidine-3-carboxamide
L444-0258 Screening compound: N-(2-methylpropyl)-1-[4-(4-propylbenzenesulfonamido)benzoyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L444-0258
N-(2-methylpropyl)-1-[4-(4-propylbenzenesulfonamido)benzoyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L444-0258

Molecular Formula

C26H35N3O4S (C26 H35 N3 O4 S)

Compound Name

N-(2-methylpropyl)-1-[4-(4-propylbenzenesulfonamido)benzoyl]piperidine-3-carboxamide

IUPAC name

N-(2-methylpropyl)-1-[4-(4-propylbenzenesulfonamido)benzoyl]piperidine-3-carboxamide

SMILES

CCCc(cc1)ccc1S(Nc(cc1)ccc1C(N(CCC1)CC1C(NCC(C)C)=O)=O)(=O)=O

InChI

InChI=1S/C26H35N3O4S/c1-4-6-20-8-14-24(15-9-20)34(32,33)28-23-12-10-21(11-13-23)26(31)29-16-5-7-22(18-29)25(30)27-17-19(2)3/h8-15,19,22,28H,4-7,16-18H2,1-3H3,(H,27,30)/t22-/m0/s1

InChI Key

JLZMWMBSPDZCEI-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD27252881

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

485.65

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.288

Distribution Coefficient, logD

3.438

Water Solubility, LogSw

-4.01

Polar Surface Area

82.155

Acid Dissociation Constant (pKa)

6.62

Base Dissociation Constant (pKb)

0.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

46.20

L444-0258 in Drug Discovery

Included in Screening Libraries

Lipid Metabolism Library (9174 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Metabolic
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with L444-0258 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L444-0258?
Check Price and Availability of L444-0258, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L444-0258 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L444-0258
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L444-0258
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L444-0258 available by request