L445-0133 Screening compound: 1-[4-(3-methoxybenzenesulfonamido)benzoyl]-N-(2-methoxyethyl)piperidine-4-carboxamide

L445-0133 Screening compound: 1-[4-(3-methoxybenzenesulfonamido)benzoyl]-N-(2-methoxyethyl)piperidine-4-carboxamide
L445-0133 Screening compound: 1-[4-(3-methoxybenzenesulfonamido)benzoyl]-N-(2-methoxyethyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L445-0133
1-[4-(3-methoxybenzenesulfonamido)benzoyl]-N-(2-methoxyethyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L445-0133

Molecular Formula

C23H29N3O6S (C23 H29 N3 O6 S)

Compound Name

1-[4-(3-methoxybenzenesulfonamido)benzoyl]-N-(2-methoxyethyl)piperidine-4-carboxamide

IUPAC name

1-[4-(3-methoxybenzenesulfonamido)benzoyl]-N-(2-methoxyethyl)piperidine-4-carboxamide

SMILES

COCCNC(C(CC1)CCN1C(c(cc1)ccc1NS(c1cc(OC)ccc1)(=O)=O)=O)=O

InChI

InChI=1S/C23H29N3O6S/c1-31-15-12-24-22(27)17-10-13-26(14-11-17)23(28)18-6-8-19(9-7-18)25-33(29,30)21-5-3-4-20(16-21)32-2/h3-9,16-17,25H,10-15H2,1-2H3,(H,24,27)

InChI Key

LSUMBTFSCVJXQB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15127732

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

475.57

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.499

Distribution Coefficient, logD

1.035

Water Solubility, LogSw

-2.61

Polar Surface Area

97.949

Acid Dissociation Constant (pKa)

7.12

Base Dissociation Constant (pKb)

4.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

L445-0133 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L445-0133 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L445-0133?
Check Price and Availability of L445-0133, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L445-0133 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L445-0133
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L445-0133
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L445-0133 available by request