L447-0299 Screening compound: 1-(4-methylphenyl)-3-(2-{5-[(propan-2-yl)sulfamoyl]-1H-1,2,3-benzotriazol-1-yl}ethyl)urea

L447-0299 Screening compound: 1-(4-methylphenyl)-3-(2-{5-[(propan-2-yl)sulfamoyl]-1H-1,2,3-benzotriazol-1-yl}ethyl)urea
L447-0299 Screening compound: 1-(4-methylphenyl)-3-(2-{5-[(propan-2-yl)sulfamoyl]-1H-1,2,3-benzotriazol-1-yl}ethyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L447-0299
1-(4-methylphenyl)-3-(2-{5-[(propan-2-yl)sulfamoyl]-1H-1,2,3-benzotriazol-1-yl}ethyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L447-0299

Molecular Formula

C19H24N6O3S (C19 H24 N6 O3 S)

Compound Name

1-(4-methylphenyl)-3-(2-{5-[(propan-2-yl)sulfamoyl]-1H-1,2,3-benzotriazol-1-yl}ethyl)urea

IUPAC name

1-(4-methylphenyl)-3-(2-{5-[(propan-2-yl)sulfamoyl]-1H-123-benzotriazol-1-yl}ethyl)urea

SMILES

CC(C)NS(c(cc1)cc2c1n(CCNC(Nc1ccc(C)cc1)=O)nn2)(=O)=O

InChI

InChI=1S/C19H24N6O3S/c1-13(2)23-29(27,28)16-8-9-18-17(12-16)22-24-25(18)11-10-20-19(26)21-15-6-4-14(3)5-7-15/h4-9,12-13,23H,10-11H2,1-3H3,(H2,20,21,26)

InChI Key

GHAILRLDIMDPLK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27253040

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.5

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.635

Distribution Coefficient, logD

2.635

Water Solubility, LogSw

-3.28

Polar Surface Area

100.599

Acid Dissociation Constant (pKa)

10.60

Base Dissociation Constant (pKb)

2.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

L447-0299 in Drug Discovery

Included in Screening Libraries

Immunological Library (6760 compounds)

PD-1/L1 Library (498 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with L447-0299 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L447-0299?
Check Price and Availability of L447-0299, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L447-0299 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L447-0299
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L447-0299
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L447-0299 available by request