L454-0234 Screening compound: 6-(4-fluorophenyl)-N-[(4-propoxyphenyl)methyl]pyridine-3-carboxamide

L454-0234 Screening compound: 6-(4-fluorophenyl)-N-[(4-propoxyphenyl)methyl]pyridine-3-carboxamide
L454-0234 Screening compound: 6-(4-fluorophenyl)-N-[(4-propoxyphenyl)methyl]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L454-0234
6-(4-fluorophenyl)-N-[(4-propoxyphenyl)methyl]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L454-0234

Molecular Formula

C22H21FN2O2 (C22 H21 FN2 O2)

Compound Name

6-(4-fluorophenyl)-N-[(4-propoxyphenyl)methyl]pyridine-3-carboxamide

IUPAC name

6-(4-fluorophenyl)-N-[(4-propoxyphenyl)methyl]pyridine-3-carboxamide

SMILES

CCCOc1ccc(CNC(c(cc2)cnc2-c(cc2)ccc2F)=O)cc1

InChI

InChI=1S/C22H21FN2O2/c1-2-13-27-20-10-3-16(4-11-20)14-25-22(26)18-7-12-21(24-15-18)17-5-8-19(23)9-6-17/h3-12,15H,2,13-14H2,1H3,(H,25,26)

InChI Key

PWXNBOOKQIBERL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27253371

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

364.42

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.880

Distribution Coefficient, logD

4.880

Water Solubility, LogSw

-4.39

Polar Surface Area

40.935

Acid Dissociation Constant (pKa)

12.44

Base Dissociation Constant (pKb)

3.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

L454-0234 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with L454-0234 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L454-0234?
Check Price and Availability of L454-0234, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L454-0234 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L454-0234
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L454-0234
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L454-0234 available by request