L454-0247 Screening compound: 6-(4-fluorophenyl)-N-[(4-methoxyphenyl)methyl]pyridine-3-carboxamide

L454-0247 Screening compound: 6-(4-fluorophenyl)-N-[(4-methoxyphenyl)methyl]pyridine-3-carboxamide
L454-0247 Screening compound: 6-(4-fluorophenyl)-N-[(4-methoxyphenyl)methyl]pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L454-0247
6-(4-fluorophenyl)-N-[(4-methoxyphenyl)methyl]pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L454-0247

Molecular Formula

C20H17FN2O2 (C20 H17 FN2 O2)

Compound Name

6-(4-fluorophenyl)-N-[(4-methoxyphenyl)methyl]pyridine-3-carboxamide

IUPAC name

6-(4-fluorophenyl)-N-[(4-methoxyphenyl)methyl]pyridine-3-carboxamide

SMILES

COc1ccc(CNC(c(cc2)cnc2-c(cc2)ccc2F)=O)cc1

InChI

InChI=1S/C20H17FN2O2/c1-25-18-9-2-14(3-10-18)12-23-20(24)16-6-11-19(22-13-16)15-4-7-17(21)8-5-15/h2-11,13H,12H2,1H3,(H,23,24)

InChI Key

SWJKWBHXRUERBY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27253381

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

336.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.903

Distribution Coefficient, logD

3.903

Water Solubility, LogSw

-4.02

Polar Surface Area

41.061

Acid Dissociation Constant (pKa)

12.44

Base Dissociation Constant (pKb)

3.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

L454-0247 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Glucocorticoid receptors Library (4806 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
Targets:
  • Kinases
  • Nuclear receptors
  • Proteases
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L454-0247 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L454-0247?
Check Price and Availability of L454-0247, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L454-0247 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L454-0247
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L454-0247
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L454-0247 available by request