L456-0119 Screening compound: 1-(4-methoxyphenyl)-4-[1-(pyridin-4-yl)piperidine-3-carbonyl]piperazine

L456-0119 Screening compound: 1-(4-methoxyphenyl)-4-[1-(pyridin-4-yl)piperidine-3-carbonyl]piperazine
L456-0119 Screening compound: 1-(4-methoxyphenyl)-4-[1-(pyridin-4-yl)piperidine-3-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L456-0119
1-(4-methoxyphenyl)-4-[1-(pyridin-4-yl)piperidine-3-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L456-0119

Molecular Formula

C22H28N4O2 (C22 H28 N4 O2)

Compound Name

1-(4-methoxyphenyl)-4-[1-(pyridin-4-yl)piperidine-3-carbonyl]piperazine

IUPAC name

1-(4-methoxyphenyl)-4-[1-(pyridin-4-yl)piperidine-3-carbonyl]piperazine

SMILES

COc(cc1)ccc1N(CC1)CCN1C(C(CCC1)CN1c1ccncc1)=O

InChI

InChI=1S/C22H28N4O2/c1-28-21-6-4-19(5-7-21)24-13-15-25(16-14-24)22(27)18-3-2-12-26(17-18)20-8-10-23-11-9-20/h4-11,18H,2-3,12-17H2,1H3/t18-/m0/s1

InChI Key

OXCYLGCQTQSHEG-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27253931

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.561

Distribution Coefficient, logD

1.957

Water Solubility, LogSw

-2.24

Polar Surface Area

40.505

Acid Dissociation Constant (pKa)

22.51

Base Dissociation Constant (pKb)

7.88

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

45.50

L456-0119 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
Structure:
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with L456-0119 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L456-0119?
Check Price and Availability of L456-0119, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L456-0119 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L456-0119
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L456-0119
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L456-0119 available by request