L456-0162 Screening compound: N~3~-{3-[4-(3-chlorophenyl)piperazino]propyl}-1-(4-pyridyl)-3-piperidinecarboxamide

L456-0162 Screening compound: N~3~-{3-[4-(3-chlorophenyl)piperazino]propyl}-1-(4-pyridyl)-3-piperidinecarboxamide
L456-0162 Screening compound: N~3~-{3-[4-(3-chlorophenyl)piperazino]propyl}-1-(4-pyridyl)-3-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L456-0162
N~3~-{3-[4-(3-chlorophenyl)piperazino]propyl}-1-(4-pyridyl)-3-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L456-0162

Molecular Formula

C24H32ClN5O (C24 H32 ClN5 O)

Compound Name

N~3~-{3-[4-(3-chlorophenyl)piperazino]propyl}-1-(4-pyridyl)-3-piperidinecarboxamide

IUPAC name

n/a

SMILES

O=C(C(CCC1)CN1c1ccncc1)NCCCN(CC1)CCN1c1cccc(Cl)c1

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.713

Distribution Coefficient, logD

2.108

Water Solubility, LogSw

-3.53

Polar Surface Area

44.550

Acid Dissociation Constant (pKa)

14.73

Base Dissociation Constant (pKb)

7.88

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

L456-0162 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Anti-Inflammatory Library (24602 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Cyclic compounds
Therapeutical areas:
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with L456-0162 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L456-0162?
Check Price and Availability of L456-0162, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L456-0162 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L456-0162
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L456-0162
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L456-0162 available by request