L457-0115 Screening compound: N~4~-(3,4-difluorophenyl)-1-(4-pyridyl)-4-piperidinecarboxamide

L457-0115 Screening compound: N~4~-(3,4-difluorophenyl)-1-(4-pyridyl)-4-piperidinecarboxamide
L457-0115 Screening compound: N~4~-(3,4-difluorophenyl)-1-(4-pyridyl)-4-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L457-0115
N~4~-(3,4-difluorophenyl)-1-(4-pyridyl)-4-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L457-0115

Molecular Formula

C17H17F2N3O (C17 H17 F2 N3 O)

Compound Name

N~4~-(3,4-difluorophenyl)-1-(4-pyridyl)-4-piperidinecarboxamide

IUPAC name

n/a

SMILES

O=C(C(CC1)CCN1c1ccncc1)Nc(cc1)cc(F)c1F

InChI

InChI=1S/C17H17F2N3O/c18-15-2-1-13(11-16(15)19)21-17(23)12-5-9-22(10-6-12)14-3-7-20-8-4-14/h1-4,7-8,11-12H,5-6,9-10H2,(H,21,23)

InChI Key

MICLUPDUOCCHIB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15128012

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

317.34

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.556

Distribution Coefficient, logD

1.951

Water Solubility, LogSw

-2.71

Polar Surface Area

36.210

Acid Dissociation Constant (pKa)

8.40

Base Dissociation Constant (pKb)

7.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

L457-0115 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
Targets:
  • Proteases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L457-0115 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L457-0115?
Check Price and Availability of L457-0115, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L457-0115 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L457-0115
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L457-0115
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L457-0115 available by request