L457-0126 Screening compound: N-(4-fluoro-2-methylphenyl)-1-(pyridin-4-yl)piperidine-4-carboxamide
Chemical Structure Depiction of ChemDiv screening compound L457-0126
N-(4-fluoro-2-methylphenyl)-1-(pyridin-4-yl)piperidine-4-carboxamide
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
L457-0126
Molecular Formula
C18H20FN3O (C18 H20 FN3 O)
Compound Name
N-(4-fluoro-2-methylphenyl)-1-(pyridin-4-yl)piperidine-4-carboxamide
IUPAC name
N-(4-fluoro-2-methylphenyl)-1-(pyridin-4-yl)piperidine-4-carboxamide
SMILES
Cc(cc(cc1)F)c1NC(C(CC1)CCN1c1ccncc1)=O
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
313.37
Hydrogen Bond Acceptors Count
3.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
4.00
Number of Nitrogen and Oxygen Atoms
4
Partition Coefficient, logP
2.517
Distribution Coefficient, logD
1.912
Water Solubility, LogSw
-2.56
Polar Surface Area
35.512
Acid Dissociation Constant (pKa)
10.04
Base Dissociation Constant (pKb)
7.88
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
33.30
L457-0126 in Drug Discovery
Included in Screening Libraries
CNS BBB Library (22607 compounds)
Integrin Receptors Targeted library (1715 compounds)
Macl-GPIb alpha Interaction Library (22969 compounds)
Protein-Protein Interaction Library (218420 compounds)
Serine Proteases Inhibitors Library (32732 compounds)
Beyond the Flatland Library sp3 enriched (92988 compounds)
Ion Channels Focused Library (26372 compounds)
Included in 1.7M Stock Database
- Nervous system
- Cancer
- Musculoskeletal
- Digestive system
- Nervous system
- Hemic and lymphatic
- Cardiovascular
- Immune system
- Hemic and lymphatic
- Cardiovascular
- Infections
- Cancer
- Musculoskeletal
- Digestive system
- Respiratory tract
- Male
- Female
- Cardiovascular
- Skin
- Metabolic
- Immune system
- Nervous system
- Cardiovascular
- Others
- Proteases
- Ion Channels
- PPI modulators
- Cyclic compounds
References: we are preparing a list of scientific research reports with L457-0126 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)