L457-0141 Screening compound: N-(4-BROMOPHENYL)-1-(PYRIDIN-4-YL)PIPERIDINE-4-CARBOXAMIDE

L457-0141 Screening compound: N-(4-BROMOPHENYL)-1-(PYRIDIN-4-YL)PIPERIDINE-4-CARBOXAMIDE
L457-0141 Screening compound: N-(4-BROMOPHENYL)-1-(PYRIDIN-4-YL)PIPERIDINE-4-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L457-0141
N-(4-BROMOPHENYL)-1-(PYRIDIN-4-YL)PIPERIDINE-4-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L457-0141

Molecular Formula

C17H18BrN3O (C17 H18 BrN3 O)

Compound Name

N-(4-BROMOPHENYL)-1-(PYRIDIN-4-YL)PIPERIDINE-4-CARBOXAMIDE

IUPAC name

N-(4-bromophenyl)-1-(pyridin-4-yl)piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c1ccncc1)Nc(cc1)ccc1Br

InChI

InChI=1S/C17H18BrN3O/c18-14-1-3-15(4-2-14)20-17(22)13-7-11-21(12-8-13)16-5-9-19-10-6-16/h1-6,9-10,13H,7-8,11-12H2,(H,20,22)

InChI Key

NFKOCYSKJMWFFJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15128028

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

360.25

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.033

Distribution Coefficient, logD

2.428

Water Solubility, LogSw

-3.08

Polar Surface Area

36.210

Acid Dissociation Constant (pKa)

10.28

Base Dissociation Constant (pKb)

7.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

L457-0141 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
Targets:
  • Proteases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L457-0141 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L457-0141?
Check Price and Availability of L457-0141, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L457-0141 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L457-0141
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L457-0141
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L457-0141 available by request