L457-0223 Screening compound: N-{[4-(propan-2-yloxy)phenyl]methyl}-1-(pyridin-4-yl)piperidine-4-carboxamide

L457-0223 Screening compound: N-{[4-(propan-2-yloxy)phenyl]methyl}-1-(pyridin-4-yl)piperidine-4-carboxamide
L457-0223 Screening compound: N-{[4-(propan-2-yloxy)phenyl]methyl}-1-(pyridin-4-yl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L457-0223
N-{[4-(propan-2-yloxy)phenyl]methyl}-1-(pyridin-4-yl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L457-0223

Molecular Formula

C21H27N3O2 (C21 H27 N3 O2)

Compound Name

N-{[4-(propan-2-yloxy)phenyl]methyl}-1-(pyridin-4-yl)piperidine-4-carboxamide

IUPAC name

N-{[4-(propan-2-yloxy)phenyl]methyl}-1-(pyridin-4-yl)piperidine-4-carboxamide

SMILES

CC(C)Oc1ccc(CNC(C(CC2)CCN2c2ccncc2)=O)cc1

InChI

InChI=1S/C21H27N3O2/c1-16(2)26-20-5-3-17(4-6-20)15-23-21(25)18-9-13-24(14-10-18)19-7-11-22-12-8-19/h3-8,11-12,16,18H,9-10,13-15H2,1-2H3,(H,23,25)

InChI Key

BYOYJKUIDONPJU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15128068

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

353.46

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.554

Distribution Coefficient, logD

1.950

Water Solubility, LogSw

-2.39

Polar Surface Area

44.335

Acid Dissociation Constant (pKa)

13.57

Base Dissociation Constant (pKb)

7.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.90

L457-0223 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

CORONAVIRUS Library (20774 compounds)

Immunological Library (6760 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Antiviral
  • Infections
  • Immune system
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
Targets:
  • Proteases
  • Others
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L457-0223 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L457-0223?
Check Price and Availability of L457-0223, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L457-0223 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L457-0223
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L457-0223
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L457-0223 available by request