L461-0169 Screening compound: N-(2-METHOXYPHENYL)-4-{[1,3]THIAZOLO[5,4-B]PYRIDIN-2-YL}-1,4-DIAZEPANE-1-CARBOXAMIDE

L461-0169 Screening compound: N-(2-METHOXYPHENYL)-4-{[1,3]THIAZOLO[5,4-B]PYRIDIN-2-YL}-1,4-DIAZEPANE-1-CARBOXAMIDE
L461-0169 Screening compound: N-(2-METHOXYPHENYL)-4-{[1,3]THIAZOLO[5,4-B]PYRIDIN-2-YL}-1,4-DIAZEPANE-1-CARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L461-0169
N-(2-METHOXYPHENYL)-4-{[1,3]THIAZOLO[5,4-B]PYRIDIN-2-YL}-1,4-DIAZEPANE-1-CARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L461-0169

Molecular Formula

C19H21N5O2S (C19 H21 N5 O2 S)

Compound Name

N-(2-METHOXYPHENYL)-4-{[1,3]THIAZOLO[5,4-B]PYRIDIN-2-YL}-1,4-DIAZEPANE-1-CARBOXAMIDE

IUPAC name

N-(2-methoxyphenyl)-4-{[13]thiazolo[54-b]pyridin-2-yl}-14-diazepane-1-carboxamide

SMILES

COc(cccc1)c1NC(N(CCC1)CCN1c1nc2cccnc2s1)=O

InChI

InChI=1S/C19H21N5O2S/c1-26-16-8-3-2-6-14(16)21-18(25)23-10-5-11-24(13-12-23)19-22-15-7-4-9-20-17(15)27-19/h2-4,6-9H,5,10-13H2,1H3,(H,21,25)

InChI Key

LMEQASBYIIPIKJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27254040

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.466

Distribution Coefficient, logD

3.422

Water Solubility, LogSw

-3.76

Polar Surface Area

55.173

Acid Dissociation Constant (pKa)

12.58

Base Dissociation Constant (pKb)

10.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.58

L461-0169 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L461-0169 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L461-0169?
Check Price and Availability of L461-0169, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L461-0169 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L461-0169
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L461-0169
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L461-0169 available by request