L461-0276 Screening compound: 1-(4-methylbenzenesulfonyl)-4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}-1,4-diazepane

L461-0276 Screening compound: 1-(4-methylbenzenesulfonyl)-4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}-1,4-diazepane
L461-0276 Screening compound: 1-(4-methylbenzenesulfonyl)-4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}-1,4-diazepane alternative view

Chemical Structure Depiction of ChemDiv screening compound L461-0276
1-(4-methylbenzenesulfonyl)-4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}-1,4-diazepane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L461-0276

Molecular Formula

C18H20N4O2S2 (C18 H20 N4 O2 S2)

Compound Name

1-(4-methylbenzenesulfonyl)-4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}-1,4-diazepane

IUPAC name

1-(4-methylbenzenesulfonyl)-4-{[13]thiazolo[54-b]pyridin-2-yl}-14-diazepane

SMILES

Cc(cc1)ccc1S(N(CCC1)CCN1c1nc(cccn2)c2s1)(=O)=O

InChI

InChI=1S/C18H20N4O2S2/c1-14-5-7-15(8-6-14)26(23,24)22-11-3-10-21(12-13-22)18-20-16-4-2-9-19-17(16)25-18/h2,4-9H,3,10-13H2,1H3

InChI Key

OUKPTVUGRCAWGD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27254079

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.608

Distribution Coefficient, logD

3.608

Water Solubility, LogSw

-3.57

Polar Surface Area

54.482

Acid Dissociation Constant (pKa)

22.60

Base Dissociation Constant (pKb)

3.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L461-0276 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L461-0276 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L461-0276?
Check Price and Availability of L461-0276, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L461-0276 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L461-0276
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L461-0276
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L461-0276 available by request